Practice 60 original MCAT questions covering biology, chemistry, psychology, CARS, and exam strategy, with answers and explanations.
Level: MCAT Medical College Admission TestDifficulty: advanced60 questions60 min
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Question 1
What is the basic unit of life?
The cell is the basic structural and functional unit of life. Atoms and molecules form cells, and organs are made of tissues.
Question 2
What is DNA made of?
DNA is a polymer of nucleotides, each with a sugar, phosphate, and nitrogenous base. Amino acids form proteins, fatty acids form lipids, and monosaccharides form carbohydrates.
Question 3
What is the main function of mitochondria?
Mitochondria generate ATP through cellular respiration. Ribosomes synthesize proteins, the nucleus stores DNA, and lysosomes break down waste.
Question 4
What is an enzyme?
Enzymes are usually proteins that catalyze reactions by lowering activation energy. Lipids store energy, carbohydrates provide structure, and nucleic acids store information.
Question 5
What is cellular respiration?
Cellular respiration breaks down glucose to produce ATP. DNA replication, protein synthesis, and cell division are separate processes.
Question 6
What is homeostasis?
Homeostasis keeps internal conditions such as temperature, pH, and glucose stable. It is not a single movement, temperature spike, or antibody response.
Question 7
What is a gene?
A gene is a DNA segment that encodes RNA or protein. Membrane proteins, lipids, and sugars are not genes.
Question 8
What is mitosis?
Mitosis produces two genetically identical somatic cells. Meiosis produces gametes, apoptosis is cell death, and folding is a protein process.
Question 9
What is the main role of the cell membrane?
The cell membrane controls transport and maintains separation. ATP production, DNA storage, and protein synthesis happen in organelles.
Question 10
What is a hormone?
Hormones are chemical messengers that coordinate physiology. Enzymes catalyze reactions, structural proteins provide support, and glycogen stores glucose.
Question 11
What is the main function of the immune system?
The immune system recognizes and attacks pathogens. Oxygen transport is red blood cells, digestion is the GI tract, and blood sugar is hormonal.
Question 12
Which process converts glucose into pyruvate?
Glycolysis converts glucose to pyruvate in the cytoplasm. The Krebs cycle and oxidative phosphorylation occur later, and gluconeogenesis builds glucose.
Question 13
What is an atom?
An atom is the smallest unit of an element with its chemical properties. Molecules, proteins, and organelles are larger structures.
Question 14
What is a covalent bond?
Covalent bonds involve shared electrons. Ionic bonds attract opposite charges, hydrogen bonds are intermolecular, and London forces are weak dispersions.
Question 15
What is an ion?
Ions form when atoms gain or lose electrons and become charged. Neutral atoms, bonds, and radioactive particles are different.
Question 16
What does pH measure?
pH indicates hydrogen ion concentration and whether a solution is acidic or basic. It does not measure temperature, mass, or pressure.
Question 17
What is stoichiometry?
Stoichiometry uses mole ratios to relate reactants and products. Kinetics studies rates, thermodynamics studies energy, and VSEPR predicts shape.
Question 18
What is enthalpy?
Enthalpy is heat content at constant pressure. Entropy measures disorder, rate measures speed, and concentration measures amount.
Question 19
What is a catalyst?
Catalysts lower activation energy and are regenerated. Reactants are consumed, products are formed, and solvents dissolve solutes.
Question 20
What is chemical equilibrium?
Equilibrium is reached when forward and reverse rates are equal, not when reactants disappear or the reaction stops.
Question 21
What is an acid according to the Brønsted-Lowry definition?
Brønsted-Lowry acids donate protons. Bases accept protons, and electron donors are reducing agents.
Question 22
What is a Brønsted-Lowry base?
Bases accept protons. Acids donate protons, and electron acceptors are oxidizing agents.
Question 23
What is oxidation?
Oxidation is the loss of electrons. Reduction is the gain of electrons, and proton or bond changes are separate concepts.
Question 24
Boyle law states that pressure and volume are inversely related at constant temperature.
Boyle law says pressure increases as volume decreases when temperature is constant. The product of pressure and volume stays constant.
Question 25
What is classical conditioning?
Classical conditioning pairs stimuli, as in Pavlov experiments. Operant conditioning uses consequences, observational learning uses models, and repetition is rehearsal.
Question 26
What is operant conditioning?
Operant conditioning changes behavior through consequences. Classical conditioning associates stimuli, observational learning watches models, and imprinting is developmental.
Question 27
What is working memory?
Working memory holds and processes current information. Long-term memory stores durable facts, sensory memory is brief, and habits are procedural.
Question 28
What is long-term memory?
Long-term memory stores information for long periods. Short-term storage lasts seconds, afterimages are sensory, and reflexes are automatic.
Question 29
What is a schema?
Schemas help organize and interpret information. Neurons, receptors, and memory cells are biological structures.
Question 30
What is attribution?
Attribution explains why behavior occurs, such as internal or external causes. Persuasion, encoding, and habit formation are different processes.
Question 31
What is conformity?
Conformity is changing behavior to fit a group. Obedience follows authority, independence resists pressure, and helping is prosocial behavior.
Question 32
What is the fight-or-flight response?
Fight-or-flight prepares the body for threat through sympathetic activation. It is not memory, digestion, or sleep.
Question 33
What is a neurotransmitter?
Neurotransmitters transmit signals across synapses. Hormones travel in blood, and proteins or sugars are not synaptic messengers.
Question 34
What is reinforcement?
Reinforcement increases behavior; punishment decreases it. Neutral stimuli and memory cues are different concepts.
Question 35
What is cognitive dissonance?
Cognitive dissonance occurs when beliefs and actions conflict, motivating consistency. It is not memory loss, learning style, or reinforcement.
Question 36
Which of the following are components of a well-designed experiment? Select all that apply.
Experiments need controls and clearly defined independent and dependent variables. Personal opinion is not an experimental component.
Question 37
What should you do first when reading a CARS passage?
Start by mapping the passage structure and main argument. Memorizing details or skipping reading leads to wrong answers.
Question 38
What is the main idea of a passage?
The main idea is the author central claim, supported by the passage. It is not one sentence, a detail, or the title alone.
Question 39
What is an author purpose?
Author purpose explains the goal, such as arguing, explaining, or evaluating. Length, citations, and vocabulary are not purposes.
Question 40
What is an inference in CARS?
Inferences go beyond the text but are supported by evidence. Direct statements, outside opinions, and unsupported guesses are not inferences.
Question 41
What is tone in a passage?
Tone reflects the author attitude, such as critical or sympathetic. Structure, length, and formatting are not tone.
Question 42
What is a counterargument?
Counterarguments present opposing views, which authors often refute. The conclusion, examples, and rhetorical questions are different.
Question 43
What is passage mapping?
Passage mapping tracks each paragraph job so you can locate evidence quickly. Word counts and highlighting are not mapping.
Question 44
What is evidence in an argument?
Evidence supports claims with facts, examples, or reasoning. Opinions, question stems, and transitions are not evidence.
Question 45
What do transition words such as however and therefore signal?
Transitions show contrast, cause, or sequence between ideas. They do not signal endings, question counts, or authorship.
Question 46
How should you handle a difficult CARS question?
Eliminating wrong choices narrows the answer using passage evidence. Length, guessing, and outside knowledge are not reliable strategies.
Question 47
What is the best way to manage CARS time?
Steady pacing prevents losing points on later passages. Rushing or over-investing harms accuracy, and question-first is not always best.
Question 48
After missing a CARS question, what should you review?
Reviewing reasoning builds transferable skills. Memorizing letters or counting words does not improve understanding.
Question 49
How many sections are on the MCAT?
The MCAT has four sections: Biological and Biochemical Foundations, Chemical and Physical Foundations, Psychological and Social Foundations, and Critical Analysis and Reasoning.
Question 50
What is the independent variable in an experiment?
The independent variable is manipulated. The dependent variable is measured, controls are held constant, and the control group receives no treatment.
Question 51
What is the dependent variable?
The dependent variable is the outcome measured. The independent variable is manipulated, constants are fixed, and random error is noise.
Question 52
What is a control variable?
Control variables are kept the same to isolate effects. Outcomes, manipulations, and confounds are different.
Question 53
What is a confound?
Confounds threaten validity by providing alternative explanations. Controlled variables are intended constants, and hypotheses or means are not confounds.
Question 54
What is the best way to use practice tests?
Timed, realistic practice plus error review builds endurance and accuracy. Open-book or selective practice hides weaknesses.
Question 55
What is spaced repetition?
Spaced repetition improves retention by scheduling reviews over time. Cramming, single readings, and highlighting are less effective.
Question 56
What should you bring on MCAT test day?
Only valid ID and AAMC-approved materials are allowed. Notes, phones, and unauthorized calculators are prohibited.
Question 57
What is the MCAT total score range?
The MCAT total score ranges from 472 to 528, with each section scored from 118 to 132. Other ranges belong to different exams.
Question 58
What is a passage-based MCAT question?
Passage-based questions use information from a passage. Standalone questions do not, and rules or surveys are not MCAT items.
Question 59
What should a strong MCAT study plan include?
Effective plans combine content, timed practice, and error analysis. Any single method leaves gaps.
Question 60
Match each MCAT section to its main focus.
The MCAT sections cover living systems, physical principles, human behavior, and reading comprehension.